pysam-developers/pysam

pysam

✅ Recently maintained

Pysam is a Python package for reading, manipulating, and writing genomics data such as SAM/BAM/CRAM and VCF/BCF files. It's a lightweight wrapper of the HTSlib API, the same one that powers samtools, bcftools, and tabix.

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Cython · MIT · Last push 2026-11-02

Official repository & installation ↗
bioinformaticsngspythonhtslib

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Provisional rubric; documentation and runtime testing are separate. Missing evidence does not imply low value.

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2025-09-292026-11-02
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Get the project

git clone https://github.com/pysam-developers/pysam.git

Cloning downloads the source. For dependencies and installation, follow the project README.

Related projects & alternative candidates

Related domains do not imply feature parity. Review official documentation and licenses.